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目的分析反复呼吸道感染患儿血清微量元素钙、铁、锌水平的变化,总结血清微量元素与呼吸道感染的关系。方法选取2013年5月至2015年5月于林州市人民医院就诊的54例反复呼吸道感染患儿作为研究对象,选取同期来院体检的50例正常健康儿童作为对照组,比较两组血清微量元素钙、铁、锌水平的差异,分析血清微量元素与反复呼吸道感染的关系。结果观察组血清锌、铁、钙水平分别为(46.21±3.58)μmol/L、(6.28±0.92)mmol/L、(1.45±0.18)mmol/L,均明显高于对照组,差异有统计学意义(P<0.05);Logistic回归分析结果显示,血钙、锌、铁水平均与小儿反复呼吸道感染存在密切关联,其中锌元素相关性最高(OR=3.652,P<0.05),其次为钙(OR=2.806,P<0.05)、铁元素(OR=2.517,P<0.05)。结论小儿呼吸道反复感染与微量元素钙、铁、锌缺乏有密切关联,补充微量元素可改善呼吸道反复感染患儿机体免疫功能。
Objective To analyze the changes of serum trace elements calcium, iron and zinc in children with recurrent respiratory tract infection and to summarize the relationship between serum trace elements and respiratory tract infection. Methods From May 2013 to May 2015, 54 children with recurrent respiratory tract infection in Linzhou People’s Hospital were enrolled. Fifty normal healthy children from the same period were selected as control group. The serum levels of trace elements Calcium, iron and zinc levels, the relationship between serum trace elements and recurrent respiratory tract infection was analyzed. Results The levels of serum zinc, iron and calcium in the observation group were (46.21 ± 3.58) μmol / L, (6.28 ± 0.92) mmol / L and (1.45 ± 0.18) mmol / L, (P <0.05). Logistic regression analysis showed that serum calcium, zinc and iron levels were closely related to recurrent respiratory tract infections in children, of which zinc was the highest (OR = 3.652, P <0.05) = 2.806, P <0.05), iron (OR = 2.517, P <0.05). Conclusion Repetitive respiratory tract infection in children is closely related to the lack of trace elements calcium, iron and zinc. Supplementation of trace elements can improve the immune function of children with recurrent respiratory tract infection.