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目的:了解重庆市宫颈癌的发病率及趋势变化,为开展宫颈癌防治工作提供建议。方法:2006至2014年的宫颈发病资料来源于重庆市肿瘤登记点,计算宫颈癌发病率、中标率、世标率、截缩率、累积率与累积危险度等指标,采用曲线估计指数分布回归模型判别趋势变化的统计学差异。结果:2006至2014年重庆市宫颈癌在女性恶性肿瘤中顺位由第6位上升至第4位,发病率、中标率与世标率分别由2006年的7.99/10万、8.52/10万、9.48/10万上升至2014年的14.82/10万、11.98/10万、12.89/10万,APC分别为7.47%、4.19%、3.77%,差异均有统计学意义(F值分别为18.32、8.38与7.40,R2分别为0.72、0.55、0.51,P值均<0.05)。宫颈癌发病率城市高于农村。农村地区发病率、中标率与世标率分别由2006年的4.53/10万、4.98/10万、5.54/10万上升至2014年的13.62/10万、12.84/10万、13.82/10万,APC分别为17.70%、13.20%、12.75%,差异均有统计学意义(F值分别为41.88、79.57与68.09,R2分别为0.86、0.92、0.91,P值均<0.001)。30岁后宫颈癌发病率随年龄增长呈上升的趋势,50岁年龄组达到高峰。2006至2014年重庆市宫颈癌截缩率、累积率与累积危险度分别由2006年的15.77/10万、0.12%、0.12%上升至2014年的25.01/10万、0.21%、0.21%,差异有统计学意义(F值分别是28.47、13.57与13.57,R2值分别为0.80、0.66、0.66,P值<0.05)。结论:重庆市宫颈癌发病率呈上升的趋势,农村宫颈癌发病率增长速度快,应加强宫颈癌的三级预防工作。
Objective: To understand the incidence and trend of cervical cancer in Chongqing, to provide recommendations for the prevention and treatment of cervical cancer. Methods: The data of cervical lesions from 2006 to 2014 were collected from Chongqing Cancer Registry. The incidence of cervical cancer, the successful rate, the world standard rate, the rate of truncation, the cumulative rate and the cumulative risk were calculated. The index was used to estimate the regression of regression Statistical Differences in Trend of Model Discrimination. Results: From 2006 to 2014, the cervical cancer in Chongqing rose from No. 6 to No. 4 in malignant tumors. The incidence, the successful rate and the standard rate were respectively 7.99 / 100000 and 8.52 / 100000 in 2006 , 9.48 / 10 million in 2014 to 14.82 / 10 million, 11.98 / 10 million and 12.89 / 10 million in 2014, with APC of 7.47%, 4.19% and 3.77% respectively. The differences were statistically significant (F values were 18.32, 8.38 and 7.40, R2 were 0.72,0.55,0.51, P <0.05). The incidence of cervical cancer in urban areas than in rural areas. In rural areas, the incidence rates, the winning rates and the world standard rates rose from 4.53 / 100,000, 4.98 / 100,000 and 5.54 / 100,000 in 2006 to 13.62 / 100,000, 12.84 / 100,000 and 13.82 / 100,000 respectively in 2014, APC were 17.70%, 13.20% and 12.75%, respectively. The differences were statistically significant (F values were 41.88, 79.57 and 68.09, R2 were 0.86, 0.92, 0.91, P <0.001 respectively). The incidence of cervical cancer after 30 years of age tends to increase with age, reaching the peak in the 50-year-old group. The rates of cervical cancer shrinkage, cumulative rate and cumulative risk in Chongqing from 2006 to 2014 increased from 15.77 / 100,000, 0.12% and 0.12% respectively in 2006 to 25.01 / 100,000, 0.21% and 0.21% in 2014, respectively (F values were 28.47, 13.57 and 13.57 respectively, R2 values were 0.80,0.66,0.66, P <0.05). Conclusion: The incidence of cervical cancer in Chongqing is on the rise. The incidence of cervical cancer in rural areas is growing rapidly. It is necessary to strengthen the tertiary prevention of cervical cancer.