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目的观察阿魏酸钠注射液治疗进展型脑梗死的疗效和安全性。方法在综合治疗基础上,将128例进展型脑梗死患者随机分为治疗组(65例)和对照组(63例),分别应用阿魏酸钠(0.3 g/d)或复方丹参注射液(16 m l/d)静脉滴注治疗,14 d为1个疗程。结果1个疗程后,两组的显效率及总有效率分别为52.3%、90.8%和28.6%、77.8%,比较差异均有统计学意义(P<0.05),不良反应均不明显。结论阿魏酸钠注射液治疗进展型脑梗死安全、有效。
Objective To observe the efficacy and safety of sodium ferulate injection in the treatment of advanced cerebral infarction. Methods On the basis of comprehensive treatment, 128 patients with progressive cerebral infarction were randomly divided into treatment group (65 cases) and control group (63 cases), and were treated with sodium ferulate (0.3 g / d) or compound Danshen injection 16 ml / d) intravenous drip treatment, 14 d for a course of treatment. Results After 1 course of treatment, the effective rates and total effective rates of the two groups were 52.3%, 90.8% and 28.6%, 77.8% respectively, with statistical significance (P <0.05). The adverse reactions were not obvious. Conclusion Sodium ferulate injection is safe and effective in the treatment of advanced cerebral infarction.