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目的观察沙培林治疗癌性胸水的临床疗效与不良反应。方法确诊肺癌患者伴胸水120例,随机分为沙培林胸腔注射组(治疗组)60例和顺铂组(对照组)60例。观察在全身化疗的基础上,沙培林对胸水的疗效。结果治疗组完全缓解有效率50%,总有效率90%;均明显高于对照组的完全缓解有效率20%及总有效率53.3%(P<0.05)。结论沙培林免疫治疗对癌性胸水具有较大的临床价值,不良反应少且轻。
Objective To observe the clinical efficacy and side effects of sapirin in the treatment of malignant pleural effusion. Methods A total of 120 patients with lung cancer and pleural effusion were randomly divided into 60 cases of CSA treated group and 60 cases of cisplatin group (control group). Observed on the basis of systemic chemotherapy, the effect of sarin on pleural effusion. Results The complete remission rate was 50% and the total effective rate was 90% in the treatment group, which were significantly higher than those in the control group (20%) and total effective rate (53.3%, P <0.05). Conclusion Sapylin immunotherapy has great clinical value for cancerous pleural effusion with less and less adverse reactions.