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本文用比较敏感的免疫细胞化学技术,研究虫草对小鼠脾脏内IgG和IgM抗体形成细胞的影响.结果发现用虫草处理7天后的小鼠,脾脏的脾小结增大,生发中心明显,边缘区增宽等反应.免疫细胞化学显示,在增大的脾小结内,有大量IgM和IgG阳性淋巴细胞,比对照组明显增加.特别是边缘区,由于IgM阳性淋巴细胞增多,致使边缘区增厚。红髓内的脾索处有大量的IgG或IgM浆母细胞或浆细胞.有的浆细胞成团存在于末端小动脉或血窦周围,它可能有利于分泌的IgG或IGM尽快进入血液循环,产生免疫反应.以上结果说明虫草能够刺激脾脏内IgG和IgM淋巴细胞增生以及促进抗体的形成.
In this paper, a relatively sensitive immunocytochemical technique was used to study the effects of Cordyceps on IgG and IgM antibody-forming cells in mouse spleens. It was found that after 7 days of treatment with Cordyceps sinensis, the spleen nodules of the spleen were enlarged and the germinal centers were prominent. Broadening and other responses. Immunocytochemistry showed that in the enlarged splenic nodules, there were a large number of IgM and IgG positive lymphocytes, which was significantly increased compared with the control group. Especially in the marginal region, the increase of IgM-positive lymphocytes caused thickening of the marginal region. . There are a large number of IgG or IgM plasmablasts or plasma cells in the splenic cord of the red pulp. Some plasma cells are clustered around the terminal arterioles or the sinusoids, which may facilitate secretion of IgG or IGM into the blood circulation as soon as possible. Produce an immune response. The above results show that Cordyceps can stimulate the proliferation of IgG and IgM lymphocytes in the spleen and promote the formation of antibodies.