论文部分内容阅读
目的探讨芬太尼或瑞芬太尼复合丙泊酚用于无痛人工流产的安全性和有效性。方法选择妇科门诊要求无痛人工流产术的健康早孕妇女80例,随机分为4组,每组20例。A组:单用丙泊酚;B组:丙泊酚加利多卡因;C组:丙泊酚加芬太尼;D组:丙泊酚加瑞芬太尼。观察各组BP、HR、SPO2、RR变化情况;以及各组在镇痛诱导时间、诱导量、用药总量、手术时间、苏醒时间等方面的差异。结果A、B两组诱导后BP、HR、SPO2、RR与诱导前比较差异有统计学意义(P<0.01);C、D两组丙泊酚总用药量明显低于A、B两组(P<0.05);且清醒时间比A、B两组快(P<0.05)。结论丙泊酚联合应用芬太尼或瑞芬太尼,用药量少,术后苏醒快,下腹痛发生率低,是一种安全、有效的麻醉方法。
Objective To investigate the safety and efficacy of fentanyl or remifentanil combined with propofol for painless induced abortion. Methods Eighty healthy pregnant women with painless artificial abortion underwent gynecological clinic were randomly divided into 4 groups with 20 cases in each group. Group A: Propofol alone; Group B: Propofol plus lidocaine; Group C: Propofol plus fentanyl; Group D: Propofol plus Remifentanil. The changes of BP, HR, SPO2 and RR in each group were observed. The differences in induction time, induction amount, total amount of medication, operation time and recovery time were also observed. Results The differences of BP, HR, SPO2 and RR between the two groups were statistically significant (P <0.01). The total dosage of propofol in group C and D was significantly lower than that of group A and B P <0.05); and awake time than A, B two groups faster (P <0.05). Conclusion Propofol combined with fentanyl or remifentanil is a safe and effective method for anesthesia with less dosage, faster recovery after surgery and lower incidence of lower abdominal pain.