由感染或非感染引发的全身炎症反应综合征(SIRS)和多脏器功能障碍综合征(MODS)是危重患者死亡的主要原因。近年来,在连续性肾替代疗法的基础上出现了一些新的技术,包括连续性血浆滤过吸附(CPFA),本文将介绍CPFA的概念及装置,并对CPFA的体外、动物和临床试验结果进行总结,进一步探讨CPFA的临床应用前景。 Systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) caused by infection or non-infection are the major causes of death in critically ill patients. In recent years, there have been some new technologies based on continuous renal replacement therapy, including continuous plasma filtration adsorption (CPFA). This article introduces the concepts and devices of CPFA, and in vitro, animal and clinical trial results of CPFA To summarize, to further explore the clinical application of CPFA prospects.