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目的:探讨胸段食管鳞癌淋巴结转移的相关影响因素。方法:筛选本院2009年1～8月行胸段食管癌根治术病例335例进行统计分析并随访术后3年内淋巴结复发的情况。结果:统计分析显示,分化程度、浸润深度、肿瘤长度对食管癌淋巴结转移的影响有统计学意义(P<0.05);食管癌发生隆突下区域淋巴结转移的比例为9.25%,随访复发比例为14.63%;随访3年淋巴结病理阳性与阴性发生淋巴结复发的比例分别为65.96%、43.98%,卡方检验χ2=13.06,P<0.05,差异有统计学意义。结论:肿瘤的分化程度越差、浸润深度越深、长度越长,淋巴结越容易发生转移;隆突下为食管癌淋巴结转移的好发区域;淋巴结转移的患者更容易出现淋巴结复发。
Objective: To investigate the related factors of lymph node metastasis in thoracic esophageal squamous cell carcinoma. Methods: A total of 335 cases of thoracic esophagectomy in our hospital from January to August 2009 were selected for statistical analysis and follow-up of lymph node recurrence within 3 years after operation. Results: Statistical analysis showed that the degree of differentiation, the depth of invasion and the length of tumor had a significant effect on the lymph node metastasis of esophageal cancer (P <0.05). The proportion of lymph node metastasis in esophageal carcinoma was 9.25% 14.63% respectively. The rates of lymph node recurrence between positive and negative lymph nodes were 65.96% and 43.98% respectively at 3 years follow-up. The chi-square test χ2 = 13.06, P <0.05, the difference was statistically significant. Conclusion: The poorer the degree of tumor differentiation, the deeper the depth of invasion, the longer the length of the lymph node is more likely to metastasize; subglottic esophageal lymph node metastasis is a good area; lymph node metastasis is more prone to lymph node recurrence.