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目的探讨心房颤动(房颤)与炎症及慢性幽门螺杆菌(Hp)感染的关系。方法选取66例房颤患者为房颤组(其中阵发性房颤44例,慢性房颤22例),另取同期住院的阵发性室上性心动过速(室上速)患者67例作为对照组,用间接ELISA法测定血清Hp-IgG抗体,速率散射免疫比浊法测定C反应蛋白(CRP),比较两组Hp-IgG抗体、CRP差异,并分析Hp抗体滴度与房颤及其他相关因素的关系。结果房颤组与对照组的Hp-IgG阳性率、Hp-IgG对数值均差异无统计学意义(P值均>0．05)。房颤组CRP中位数较对照组高(1．17 mg／dL比0．65mg／dL,P<0．05)。结论房颤与慢性Hp感染无关,与炎症相关。
Objective To investigate the relationship between atrial fibrillation (AF) and inflammation and chronic Helicobacter pylori (Hp) infection. Methods Sixty-six AF patients (AF, 44 with paroxysmal atrial fibrillation and 22 with chronic atrial fibrillation) were enrolled in this study. Sixty-seven patients with paroxysmal supraventricular tachycardia Serum Hp-IgG antibody was detected by indirect ELISA and C-reactive protein (CRP) by rate nephelometry. The differences of Hp-IgG antibody and CRP between the two groups were compared. The relationship between Hp antibody titers and atrial fibrillation Other related factors. Results There was no significant difference in Hp-IgG positive rate and Hp-IgG logarithm between AF group and control group (P> 0.05). The median CRP in AF group was higher than that in control group (1.17 mg / dL vs 0.65 mg / dL, P <0.05). Conclusion Atrial fibrillation has no relation with chronic Hp infection and is related to inflammation.