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Purpose:To compare the efficacy of quadratus femoris muscle pedicle bone flap transplantation combined with hollow compression screw fixation versus AO hollow compression screw fixation in the treatment of femoral neck fracture for Chinese young and middle-aged patients.Methods:Case-controlled studies (CCTs) were used to compare the two operative methods in the treatment of femoral neck fractures.Data were retrieved from the Cochrane Library,Pubmed Database,CNKI,Chinese Biomedical Database.Wanfang Data published during the period of January 2005 to December 2014.Methodological quality of the trials was critically assessed,and relevant data were extracted.Statistical Software Revman 5.0 wasused for data-analysis.Results:Eight articles were included in the meta-analysis.The results showed that there was statistical significance in the rate of fracture healing [OR =5.43,95％ CI (2.89,10.20),p ＜ 0.05],the rate of good function of hip joint [OR =5.12,95％ CI (3.21,8.17),p ＜ 0.05],the rate of femoral head necrosis [OR =4.21,95％ CI(2.02,8.76),p ＜ 0.05],the time of fracture healing [WMD =-46.85,95％ CI(-65.13,-28.56),p ＜ 0.05] between the two groups.Conclusions:For the treatment of femoral neck fractures,the transplantation of quadratus femoris muscle pedicle bone flap combined with hollow compression screw;fixation is superior to the AO hollow compression screw fixation in terms of the rate;of fracture healing,the rate of good function of hip joint,the rate of femoral head;necrosis and the time of fracture healing.