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血清铁蛋白是一种含铁的高分子量蛋白质,是体内贮藏铁的复合物。我院于1982年建立了酶联免疫血铁蛋白测定法。初步观察结果,缺铁性贫血患者的血清铁蛋白值明显低于正常值(P<0.001),营养性巨幼红细胞性贫血和再障患者的血清铁蛋白值明显高于正常值。本文的目的拟探讨:①血清铁蛋白测定在缺铁性贫血中的诊断价值;②和体内铁贮存无关因素对血清铁蛋白测定数值的影响;③铁剂治疗后不同的血清铁蛋白值能否反映骨髓细胞外铁的不同等级。并就有关文献作一复习。
Serum ferritin is a high-molecular-weight iron-containing protein that stores iron in the body. Our hospital established in 1982 enzyme-linked immune ferritin assay. Preliminary observations showed that serum ferritin was significantly lower in patients with iron-deficiency anemia (P <0.001), serum ferritin values were significantly higher in patients with nutritional megaloblastic anemia and aplastic anemia. The purpose of this paper is to explore: ① serum ferritin in the diagnosis of iron deficiency anemia; ② and iron storage in vitro factors unrelated to the determination of serum ferritin values; ③ iron after treatment of different serum ferritin values can Reflect different levels of bone marrow extracellular iron. And make a review of the literature.