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目的:优选出健脾温胃胶囊剂的最佳提取工艺。方法:以处方中党参炔苷的含量和浸膏收率作为优选评价指标,采用正交试验设计法优选健脾温胃胶囊剂的提取工艺条件。结果:最佳提取工艺条件为加8倍量的水,回流提取3次,每次1 h;采用低压真空浓缩干燥法(温度60℃,真空度在0.07~0.08MPa)对提取液进行浓缩、干燥。结论:最佳提取工艺条件提取效率高,稳定性和重复性好,可作为健脾温胃胶囊剂的提取工艺。
Objective: To optimize the extraction process of Jianpiweweng capsule. Methods: The content of ginsenoside in the prescription and the yield of extract were chosen as the evaluation indexes. The orthogonal experimental design method was adopted to optimize the extraction process of Jianpiweiguan Capsule. Results: The optimal extraction conditions were as follows: adding 8 times the amount of water and refluxing for 3 times, each time being 1 h; using low pressure vacuum concentration drying method (temperature 60 ℃, vacuum 0.07 ~ 0.08MPa) dry. Conclusion: The best extraction conditions extraction efficiency, stability and reproducibility, and can be used as the extraction process of Jianpiweiguan capsules.