维生素D对人体的生长、代谢和免疫具有重要作用,缺乏维生素D易引起佝偻病。艾滋病病毒(HIV)严重威胁人类健康,而HIV感染者体内的维生素D水平普遍偏低。近期研究发现,维生素D诱导细胞发生自噬,提高抗菌肽表达,对HIV病毒复制起抑制作用。利用维生素D制剂辅助治疗HIV疾病具有潜在的临床应用价值。 Vitamin D on the human body’s growth, metabolism and immune have an important role, the lack of vitamin D can cause rickets. HIV is a serious threat to human health, while the level of vitamin D in HIV-infected people is generally low. Recent studies have found that vitamin D induces autophagy in cells, enhances the expression of antimicrobial peptides, and inhibits HIV virus replication. The use of vitamin D preparations for the treatment of HIV disease has potential clinical value.