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目的 探讨儿童单纯性肥胖症胰岛素抵抗及血脂变化。方法 30例肥胖儿来自 1995年 7月～ 1998年 5月儿科门诊 ,另选 2 0例无内分泌紊乱及代谢性疾病和肝肾功能正常的非肥胖儿作对照组。均晨空腹抽血测胰岛素、血糖、胆固醇、三酸甘油酯、游离脂肪酸。结果 肥胖组空腹胰岛素、胆固醇、三酸甘油酯、游离脂肪酸值明显高于对照组 (P<0 .0 1) ,肥胖组与对照组空腹血糖无差异 (P>0 .0 5 )。结论 单纯性肥胖儿常伴有高胰岛素血症及高血脂症。
Objective To investigate the changes of insulin resistance and blood lipid in children with simple obesity. Methods Thirty cases of obese children were selected from pediatric outpatients from July 1995 to May 1998, and another 20 non-obese children without endocrine disorders and metabolic diseases and normal liver and kidney function were selected as the control group. Morning fasting blood test insulin, blood sugar, cholesterol, triglycerides, free fatty acids. Results Fasting insulin, cholesterol, triglyceride and free fatty acid in obese group were significantly higher than those in control group (P <0.01). There was no difference in fasting blood glucose among obese group and control group (P> 0.05). Conclusion Simple obesity often accompanied by hyperinsulinemia and hyperlipidemia.