1806年Alibert首先描述蕈样霉菌病(MF)且指出本病巨体表现呈蕈样病变。1868年Gillot指出MF是淋巴系统的疾病。现在认为MF是皮肤的T淋巴细胞的恶性肿瘤。本病的早期阶段虽有很长的病程,如不进行适当的治疗,大多数病人最终都发展为广泛的皮肤肿瘤以及皮肤外的播散,可累及淋巴结、骨髓以及内脏,最终导致病人死亡。这种肿瘤对放射线极敏感。过去最常采用 In 1806 Alibert first described mycosis fungoides (MF) and pointed out that the disease’s giant body showed a club-like lesion. In 1868 Gillot pointed out that MF is a disease of the lymphatic system. It is now believed that MF is a malignant tumor of T lymphocytes of the skin. Although the early stages of the disease have a long course of disease, most patients eventually develop extensive skin tumours and dissemination outside the skin. This can involve lymph nodes, bone marrow, and internal organs, leading to death. This tumor is extremely sensitive to radiation. Used most often in the past