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目的探讨匹维溴铵联合氟哌噻吨美利曲辛治疗肠易激综合征的临床疗效。方法选取2014年4月至2016年5月肠易激综合征患者50例,将其随机分成两组,每组25例。对照组口服匹维溴铵片治疗,观察组在对照组基础上加服氟哌噻吨美利曲辛片治疗。比较两组治疗效果。结果对照组各项症状积分明显高于观察组,差异有统计学意义(P<0.05);对照组总有效率(68.00%)明显低于观察组(92.00%),差异有统计学意义(P<0.05);对照组患者SDS和SAS评分明显高于观察组,差异有统计学意义(P<0.05)。结论匹维溴铵联合氟哌噻吨美利曲辛治疗肠易激综合征疗效确切,能明显缓解患者临床症状,改善患者心理状态,加速患者康复进程,具有较高的临床应用价值。
Objective To investigate the clinical efficacy of pinaverium bromide combined with flupenthixol and melitracen in the treatment of irritable bowel syndrome. Methods 50 patients with irritable bowel syndrome from April 2014 to May 2016 were selected and randomly divided into two groups (n = 25 in each group). The control group was treated with pinaverium bromide tablets, and the observation group was treated with flupentixol and melitracen tablets on the basis of the control group. Compare the treatment effect of two groups. Results The symptom score of the control group was significantly higher than that of the observation group (P <0.05). The total effective rate (68.00%) in the control group was significantly lower than that of the observation group (92.00%) (P <0.05). SDS and SAS scores in the control group were significantly higher than those in the observation group (P <0.05). Conclusions Pivivirin combined with flupentixol and melitracen can effectively relieve irritable bowel syndrome and relieve clinical symptoms, improve the psychological status of patients and accelerate the recovery of patients with high clinical value.