论文部分内容阅读
目的探讨慢性肾脏病(CKD)患者血压控制情况以及影响血压达标的因素。方法采用单中心、前瞻性队列研究方法,入选260例CKD患者,按照《慢性肾脏病及透析的临床实践指南》(K/DOQI指南)对入选患者进行血压干预,随访1年,然后评价患者的血压改善情况,分析影响血压控制的因素。结果 CKD患者血压的降低与蛋白尿的降低有关。logistic回归分析发现尿蛋白含量≥1.0 g/24 h、基线收缩压高和基线舒张压高是血压未达标组的独立影响因子;文化水平高是血压达标组的独立影响因子。结论 CKD患者的血压经过肾病学专家的调理有望得到改善。高的基线血压和尿蛋白水平(≥1.0 g/24 h)是影响血压达标的主要因素。
Objective To investigate the blood pressure control in patients with chronic kidney disease (CKD) and the factors that affect blood pressure compliance. Methods A single-center, prospective cohort study was conducted in 260 patients with CKD. Blood pressure was administered to selected patients according to the Kinetic Guidelines for Chronic Kidney Disease and Dialysis (K / DOQI guidelines), followed up for 1 year. Patients were then evaluated Improve blood pressure, analyze factors that affect blood pressure control. Results The decrease of blood pressure in CKD patients was associated with the decrease of proteinuria. Logistic regression analysis showed that urinary protein content≥1.0 g / 24 h, baseline systolic blood pressure and baseline diastolic blood pressure were independent influencing factors of blood pressure non-compliance group; high cultural level was the independent influencing factor of blood pressure compliance group. Conclusions Blood pressure in CKD patients is expected to be improved by nephrologists. High baseline blood pressure and urinary protein levels (≥ 1.0 g / 24 h) are the major factors that affect blood pressure compliance.