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目的:评价稳心颗粒干预蒽环类化疗药物引起心律失常的疗效。方法:将手术切除后经病理证实为恶性肿瘤者随机分为A组(治疗组)共38例,B组(单纯化疗组)共34例,给予含蒽环类抗肿瘤药物联合全身化疗及采用稳心颗粒5g,每日3次温水冲服。结果:A、B两组差异无统计学意义(P>0.05),A、B两组心律失常差异有统计学意义(P<0.05)。结论:稳心颗粒可以减轻蒽环类化疗药物近期心律失常毒性反应,值得临床应用。
Objective: To evaluate the effect of Wenxin granule on anthracycline-induced arrhythmia. Methods: Thirty-eight cases were randomly divided into group A (treatment group) and group B (chemotherapy alone group), 34 cases were treated with anthracycline antineoplastic agents and systemic chemotherapy Wenxin particles 5g, 3 times a day warm water blunt. Results: There was no significant difference between A and B groups (P> 0.05). There was significant difference in arrhythmia between groups A and B (P <0.05). Conclusion: Wenxin Granule can reduce the recent arrhythmic toxicity of anthracycline chemotherapy, which is worthy of clinical application.