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目的探讨急性期脑卒中患者入院时平均动脉压(MAP)与其住院期间死亡、残疾危险性之间的关系。方法回顾性分析2003-01-2005-12内蒙古通辽市6家医院的3938例脑卒中患者的入院血压、血脂、血糖、疾病史以及住院期间死亡和残疾资料,采用Logistic回归模型,对入院血压与急性脑卒中患者住院期间死亡和残疾的关系进行统计分析,计算OR和95%CI。结果在出血性脑卒中患者中,调整了年龄、性别、民族、吸烟、饮酒、血脂和血糖因素后,与MAP<103 mm Hg者相比,MAP≥133 mm Hg者的死亡OR值为2.12,MAP在103～116、117～132和MAP≥133 mm Hg者的残疾OR值分别为1.85、2.15和1.99(均P<0.01)。在缺血性脑卒中患者中,各组的死亡和残疾的OR均无统计学意义。结论急性出血性脑卒中患者入院时MAP越高,其发生死亡和残疾的危险性越大。
Objective To investigate the relationship between mean arterial pressure (MAP) at hospital admission and the risk of death and disability during hospitalization in acute stroke patients. Methods A retrospective analysis of admission blood pressure, blood lipids, blood glucose, disease history and death and disability data of 3938 stroke patients from 6 hospitals in Tongliao City, Inner Mongolia from January to December 2005 was conducted. Logistic regression model was used to analyze the relationship between admission blood pressure and Acute stroke patients were hospitalized during the death and disability statistical analysis, calculated OR and 95% CI. Results In hemorrhagic stroke patients, the odds ratio for death in patients with MAP ≥ 133 mm Hg was 2.12 after adjustment for age, gender, ethnicity, smoking, alcohol consumption, lipids, and blood glucose compared with patients with MAP <103 mm Hg, The ORs of patients with MAP at 103 ~ 116, 117 ~ 132 and MAP ≥ 133 mm Hg were 1.85, 2.15 and 1.99 (all P <0.01). In ischemic stroke patients, there was no significant difference in OR between death and disability in each group. Conclusion The higher the MAP at admission, the greater the risk of death and disability in acute hemorrhagic stroke patients.