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呼吸机相关肺炎(VAP)是机械通气(MV)患者常见并发症,是导致其病死率增加、住院时间及费用增加的主要原因,而部分患者并发的医院内气管支气管炎(NTB)可能是发生VAP的前奏[1]。MV患者在气管导管(ETT)内形成的细菌生物被膜(BF)是VAP的重要致病菌来源之一,有关抑制ETT-BF形成而降低
Ventilator-associated pneumonia (VAP) is a common complication in patients with mechanical ventilation (MV), leading to increased mortality and longer hospital stays and costs, and some patients with concurrent hospitalized tracheobronchitis (NTB) may be the cause Prelude to VAP [1]. Bacterial biofilms (BFs) formed in endotracheal tubes (ETTs) in MV patients are one of the most important sources of pathogens in VAPs and are associated with reduced ETT-BF formation