论文部分内容阅读
目的:研究anti-TgAb和anti-TPOAb在自身免疫性甲状腺疾病中的诊断价值。方法:分析在本院乳甲科就诊的171例患者资料,分为桥本甲状腺炎(HT)组,Graves组,结节性甲状腺肿组,甲状腺腺瘤组和甲状腺乳头状瘤组。化学免疫发光分析法测定血清anti-TgAb和anti-TPOAb,40例健康体检者为正常对照。结果:HT组和Graves组anti-TgAb和anti-TPOAb均高于其他4组(P<0.05);HT组anti-TgAb大于正常值1、3倍,Graves组大于正常值1倍和两组anti-TPOAb大于正常值1、3、10倍例数均高于其他4组(P<0.05);HT组和Graves组两项都大于参考值1、3倍的数量高于其余各组(P<0.05)。而HT组和Graves组间的差异无统计学意义(P>0.05)。结论:血清anti-TgAb和anti-TPOAb测定值的增高对HT和Graves的诊断有意义。
Objective: To investigate the diagnostic value of anti-TgAb and anti-TPOAb in autoimmune thyroid diseases. Methods: The data of 171 patients treated in our department were divided into Hashimoto’s thyroiditis (HT) group, Graves group, nodular goiter group, thyroid adenoma group and thyroid papillary tumor group. Serum anti-TgAb and anti-TPOAb were measured by chemiluminescence immunoassay, and 40 healthy controls were normal controls. Results: The anti-TgAb and anti-TPOAb in HT group and Graves group were higher than those in the other four groups (P <0.05). The anti-TgAb in HT group was 1,3 times higher than that in normal group and 1 times higher than normal in Graves group -TPOAb were higher than the normal 1,3,10-fold higher than the other four groups (P <0.05); HT and Graves group two were greater than the reference value of 1,3 times higher than the other groups (P < 0.05). There was no significant difference between HT group and Graves group (P> 0.05). Conclusion: The increase of serum anti-TgAb and anti-TPOAb values is of significance for the diagnosis of HT and Graves.