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目的对比中西医结合与单纯西药治疗ICU重症肺部感染在治疗效果方面的差异,探讨重要辅助治疗的应用价值。方法选择2012年1月——2014年1月间收治的100例ICU重症肺部感染患者为研究对象,随机分为观察组和对照组各50例患者。对照组患者采用常规西药治疗,观察组患者在接受与对照组患者完全相同的西药治疗的基础上接受中药治疗,痰热清注射液20ml静脉滴注,1次/d。连续治疗两周,对比两组患者的治疗效果,计数资料采用χ2检验,计量资料比较采用t检验,P<0.05为差异有统计学意义。结果经过治疗,观察组治疗为有效率92.00%,高于对照组的78.00%,两组间治疗有效率的差异有统计学意义(P<0.05);治疗前,两组患者在白细胞总数、Pa O2、Pa CO2、Sa O2方面的差异不具有统计学意义(P>0.05)。观察组治疗后Pa O2、Pa CO2、Sa O2分别为(11.34±0.57)、(5.89±0.27)KPa和(97.12±0.93)%,对照组分别为(9.68±0.46)、(4.54±0.21)KPa和(90.47±0.68)%,观察组显著高于对照组,差异有统计学意义(P<0.05)。治疗中,两组均无与药物治疗直接关联的不良反应病例。结论中西医结合治疗ICU重症肺部感染,发挥了中药的辅助作用,改善了患者症状、体征,提升了治疗效果。
Objective To compare the difference between the treatment effect of Integrative Medicine and western medicine in the treatment of ICU severe pulmonary infection and to explore the value of important adjuvant therapy. Methods A total of 100 ICU patients with severe pulmonary infection who were admitted between January 2012 and January 2014 were selected and randomly divided into observation group and control group with 50 patients each. Patients in the control group were treated with conventional western medicine. The patients in the observation group were treated with traditional Chinese medicine on the basis of exactly the same western medicine as those in the control group. Infused with 20 ml of Tanreqing injection once a day. Continuous treatment for two weeks, compared the two groups of patients, the count data using χ2 test, measurement data using t test, P <0.05 for the difference was statistically significant. Results After treatment, the effective rate of the observation group was 92.00%, which was higher than that of the control group (78.00%), the difference between the two groups was statistically significant (P <0.05); before treatment, the total number of leukocytes, Pa O2, Pa CO2, Sa O2 differences were not statistically significant (P> 0.05). PaO2, PaCO2 and Sa O2 in the observation group were (11.34 ± 0.57) and (5.89 ± 0.27) KPa and (97.12 ± 0.93)%, respectively, and those in the control group were (9.68 ± 0.46) and (4.54 ± 0.21) KPa And (90.47 ± 0.68)%, the observation group was significantly higher than the control group, the difference was statistically significant (P <0.05). In the treatment group, there were no adverse reactions directly associated with drug treatment in both groups. Conclusion Integrative Chinese and Western medicine treatment of ICU severe lung infection, play a supporting role of traditional Chinese medicine to improve the symptoms and signs of patients and improve the therapeutic effect.