目的、方法及结果：本文报告用快速纸试剂对１０１２例有上消化道症状４０岁以上，７０岁以下患者幽门螺杆菌感染情况，总感染率５６％，其中活动性慢性胃炎、胃溃疡、十二指肠球部溃疡及复合性溃疡ＨＰ感染率分别为８５．９％、６２．１％、５２．８％、７０．３％，明显高于非活动性慢性胃炎（２５．１％）及胃癌（２３．５％），Ｐ＜０．０１。结论：提示ＨＰ感染具有致病性、与活动性慢性胃炎及消化性溃疡有密切关系，并可能是胃癌发生的重要因素 PURPOSE, METHODS AND RESULTS: This paper reports the prevalence of Helicobacter pylori infection in 1012 patients with upper gastrointestinal symptoms over the age of 40 and under 70 years with a rapid paper reagent, with a total infection rate of 56%, of which active chronic gastritis, gastric ulcer, The HP infection rates of duodenal ulcer and composite ulcer were 85.9%, 62.1%, 52.8% and 70.3%, respectively, which were significantly higher than those of inactive chronic gastritis (25.1%) and Gastric cancer (23.5%), P <0.01. Conclusion: It is suggested that HP infection is pathogenic, closely related to active chronic gastritis and peptic ulcer, and may be an important factor in the occurrence of gastric cancer