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目的观察西格列汀联合二甲双胍对2型糖尿病的临床疗效。方法选取2016年2月-2017年1月在医院接受治疗的2型糖尿病患者30例,予西格列汀联合二甲双胍方案治疗,12周后分析比较比较用药前后空腹血糖(FBG)、餐后2h血糖(2h PG)、糖化血红蛋白(Hb A1c)变化情况。结果治疗12周后患者的空腹血糖、餐后2h血糖、糖化血红蛋白等相比治疗前均有明显下降,差异有统计学意义(P<0.05)。结论西格列汀联合二甲双胍在2型糖尿病患者中有较好治疗效果,值得在临床中不断推广和运用。
Objective To observe the clinical effect of sitagliptin and metformin on type 2 diabetes mellitus. Methods Thirty patients with type 2 diabetes treated in the hospital from February 2016 to January 2017 were treated with sitagliptin and metformin. After 12 weeks, fasting blood glucose (FBG), fasting plasma glucose Blood glucose (2h PG), glycosylated hemoglobin (Hb A1c) changes. Results After 12 weeks of treatment, the fasting blood glucose, postprandial blood glucose 2h, glycosylated hemoglobin, etc. were significantly lower than before treatment, the difference was statistically significant (P <0.05). Conclusion Sitagliptin combined with metformin in patients with type 2 diabetes have a better therapeutic effect, it is worth in the clinic continue to promote and use.