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目的:探讨腹腔镜肾上腺切除术在多发性内分泌肿瘤综合征-2A型患者中的有效性与安全性。方法:回顾性分析2015年12月~2016年5月于我院诊断为多发性内分泌肿瘤综合征-2A型的4例患者资料,患者均接受腹腔镜下肾上腺切除术。结果:男1例,女3例,平均年龄36(27~56)岁。基因检测分析均提示:RET原癌基因突变。4例患者手术均顺利完成,无一例中转开放手术。手术时间平均为45(30~90)min。术中平均失血为17.75(15~30)ml,术中、术后无严重并发症。平均住院时间30.75(22~36)d,泌尿外科平均住院时间9.25(7~14)d。随访1~6个月,未见复发。结论:多发性内分泌肿瘤综合征-2A型患者应用腹腔镜肾上腺手术有效、安全。
Objective: To investigate the effectiveness and safety of laparoscopic adrenalectomy in patients with multiple endocrine neoplasia syndrome type-2A. Methods: The data of 4 patients with multiple endocrine neoplasia syndrome type-2A diagnosed in our hospital from December 2015 to May 2016 were retrospectively analyzed. All patients underwent laparoscopic adrenalectomy. Results: There were 1 males and 3 females with an average age of 36 (27 ~ 56) years. Genetic testing and analysis all suggest: RET protooncogene mutation. All 4 patients completed the operation successfully, and none of them underwent open surgery. The average operation time was 45 (30-90) min. Intraoperative mean blood loss was 17.75 (15 ~ 30) ml, intraoperative and postoperative no serious complications. The average length of hospital stay was 30.75 (22-36) days, and urology average length of stay was 9.25 (7-14 days). Follow-up 1 ~ 6 months, no recurrence. Conclusions: Laparoscopic adrenalectomy is effective and safe in patients with multiple endocrine neoplasia syndrome type-2A.