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目的:探讨复方米非司酮与米非司酮用于终止早孕的效果。方法:停经≤49天的早孕妇女80例,随机平分为两组,A组服复方米非司酮,1片/24h,连用2天;B组服米非司酮,1片/12h,连服3天,两组均于前一药物服完第2天服米索前列醇600μg,观察孕囊排出情况、出血时间、出血量及服药后的副反应,了解转经情况。结果:A、B两组完全流产率和胃肠道副反应发生率比较均无显著差异。孕囊排出时间和转经时间A、B两组间比较有显著差异(P<0.05)。结论:复方米非司酮与米非司酮相比可加速孕囊排出,减少出血量和出血时间,提高完全流产效果。
Objective: To investigate the effect of compound mifepristone and mifepristone on termination of early pregnancy. Methods: Eighty pregnant women with menopause ≤ 49 days were randomly divided into two groups. Group A received mifepristone, 1 tablet / 24h for 2 days. Group B received mifepristone, 1 tablet / 12h, For 3 days, both groups took 600 μg of misoprostol on the second day of the previous drug service, and observed the discharge of the gestational sac, the bleeding time, the amount of bleeding and the side effects after taking the drug, so as to understand the situation of the trans-menstrual cycle. Results: There was no significant difference in the rates of complete abortion and gastrointestinal side effects between groups A and B. The gestational sac drainage time and the transit time A, B were significantly different between the two groups (P <0.05). Conclusion: Compared with mifepristone, mifepristone can accelerate the discharge of gestational sac, reduce the amount of bleeding and bleeding time and improve the effect of complete abortion.