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目的:探讨糜蛋白酶、高渗糖配伍胰岛素治疗腹部切口愈合不良的效果。方法:对18例妇产科手术后腹部切口愈合不良病例的诊断、体征、特殊情况及处理方法、愈合情况等临床资料进行回顾性分析,采用局部清创,创面覆盖糜蛋白酶,切口注射高渗糖胰岛素,并用普通医用胶布闭合切口。结果:脂肪液化、感染、营养不良、缝合不当为腹壁切口愈合不良的主要因素,经糜蛋白酶清创、创面局部注射高糖胰岛素后,封闭5～7 d全部治愈,切口愈合率100%。结论:糜蛋白酶、高渗糖配伍胰岛素对治疗腹部切口愈合不良有良好的效果,且方法简单易行,见效快,花费少,患者痛苦小,易被接受。
Objective: To investigate the effect of chymotrypsin and hypertonic glucose in combination with insulin in the treatment of abdominal incision healing. Methods: The clinical data of 18 cases of poor incision healing after obstetrics and gynecology surgery were retrospectively analyzed. The clinical data including local debridement, chymotrypsin wound coverage and incision injection hyperosmolarity Sugar insulin, and closed with ordinary medical tape incision. Results: Limp liquefaction, infection, malnutrition and improper suture were the main factors for poor healing of abdominal incision. After chymotrypsin debridement and topical injection of high glucose insulin, the wounds were completely closed from 5 to 7 days and the incision healing rate was 100%. Conclusion: The combination of chymotrypsin and hypertonic glucose with insulin has a good effect on the treatment of poor incision of abdominal incision. The method is simple and easy to operate, quick and inexpensive, less painful and easy to be accepted.