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勒雪氏病为组织细胞增生症X中的一型,本文报告34例勒雪氏病,男女各17例,年龄为2个月至2岁9个月,出现症状最早者为生后1个月,发病就诊最长者15个月。临床有发热(100%),皮疹(100%),咳嗽(94.1%),腹泻(47%),中耳炎(44.1%),苍白(94.1%),喘促,发绀,纳差等。查体主要为肝脾淋巴结肿大及发育迟缓等。本组合并肺炎9例,心力衰竭6例。呼吸衰竭6例,败血症1例。胸部摄片33例,示网状、小点片、斑片、结节状影及肺纹理增粗,透过度减低等32例,正常1例。血象:血红蛋白<120g/L30例,白细胞(2.6~95.2)×10~9/L,BPC<100×10~9/L25例。皮疹印片均见大量组织细胞增生。
Leser’s disease is a type of histiocytosis X, this article reports 34 cases of Leucosis, males and females of 17 cases, aged 2 months to 2 years and 9 months, the first symptoms after the birth of a Month, onset of treatment for the longest 15 months. Clinical fever (100%), rash (100%), cough (94.1%), diarrhea (47%), otitis media (44.1%), paleness (94.1%), wheezing, cyanosis, anorexia and so on. Physical examination for liver and spleen lymph nodes and growth retardation. This group of 9 cases of pneumonia, heart failure in 6 cases. Respiratory failure in 6 cases, 1 case of sepsis. 33 cases of chest radiography, showing reticular, dot film, patch, nodular shadow and lung texture thickening, reduced permeability in 32 cases, normal in 1 case. Blood: Hemoglobin <120g / L30 cases, white blood cells (2.6 ~ 95.2) × 10 ~ 9 / L, BPC <100 × 10 ~ 9 / L25 cases. Rash prints were seen a large number of cell proliferation.