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目的分析本院麻醉药品在肿瘤镇痛中的使用情况。方法选取溧阳市人民医院2014年2月—2014年9月收治的癌痛患者85例,用于肿瘤镇痛的麻醉药物处方203张。统计分析患者的年龄、诊断及药品种类、用量、用药次数及不合理处方。结果在85例癌痛患者中男59例,女26例;年龄主要分布在42~77岁,在各个年龄段中男性患者多于女性患者。在203张麻醉药品处方中包括2种口服药物:可待因片84张(41.4%)、美施康定16张(7.9%);3种注射剂:哌替啶32张(15.8%)、吗啡针17张(8.4%)、布桂嗪14张(6.9%);2种外用贴剂:芬太尼透皮贴(杨森)9张(4.4%)、瑞芬太尼透皮贴(常州)8张(3.9%)。85例癌痛患者中,胃癌34例,主要使用可待因片、哌替啶、吗啡及美施康定镇痛;肺癌21例,主要使用可待因片、吗啡镇痛;肝癌18例,主要使用可待因片、哌替啶、布桂嗪及芬太尼镇痛;胰腺癌12例,主要使用可待因片、布桂嗪、吗啡镇痛。口服药物:可待因片30 mg、美施康定10 mg和30 mg;注射药剂:哌替啶100 mg、吗啡针10 mg、布桂嗪100 mg;外用贴剂:芬太尼透皮贴(杨森)4.2 mg;瑞芬太尼透皮贴(常州)2.5 mg。7种麻醉药品中,可待因片使用84次,哌替啶使用32次,芬太尼使用19次,吗啡针使用17次,美施康定使用16次,布桂嗪使用14次。203张处方中,处方不合理率为11.3%。结论本院肿瘤镇痛用麻醉用药基本合理,处方管理尚有欠缺,需进一步完善。麻醉药品是一种特殊管理药品,医师和药师需严格按照规定实施相关管理,减少麻醉药品的使用问题,提高麻醉用药管理质量。
Objective To analyze the use of anesthesia in our hospital for analgesia. Methods 85 cases of cancer pain patients treated in Liyang People’s Hospital from February 2014 to September 2014 were selected and 203 prescriptions for narcotic drugs for tumor pain were selected. Statistical analysis of the patient’s age, diagnosis and type of drug, dosage, frequency of medication and unreasonable prescription. Results There were 59 males and 26 females with cancer in 85 cases. The age was mainly in the range of 42-77 years. There were more males than females in all age groups. Two oral medications were included in the 203 narcotic prescriptions: 84 (41.4%) of codeine and 16 (7.9%) of mesylicitine; three injections: 32 pethidine (15.8%), morphine needle 17 (8.4%) and 14 (6.9%) buzauciurin; two topical patches: 9 fentanyl transdermal patches (4.4%), remifentanil transdermal patch (Changzhou) 8 Zhang (3.9%). Of the 85 patients with cancer pain, 34 cases were gastric cancer, and mainly used codeine, meperidine, morphine and midazolam analgesia; 21 cases of lung cancer, mainly using codeine, morphine analgesia; liver cancer in 18 cases, mainly The use of codeine, pethidine, buprofezin and fentanyl analgesia; pancreatic cancer in 12 cases, the main use of codeine, buprofezin, morphine analgesia. Oral drugs: Codeine 30 mg, Meiscostein 10 mg and 30 mg; Injection: Pethidine 100 mg, Morphine needle 10 mg, Buzurin 100 mg; External patch: Fentanyl transdermal patch Janssen) 4.2 mg; Remifentanil transdermal (Changzhou) 2.5 mg. Of the seven narcotic drugs, 84 were used for codeine, 32 for pethidine, 19 for fentanyl, 17 for morphine, 16 for mesylate, and 14 for bucunazine. Of 203 prescriptions, the unreasonable rate of prescription was 11.3%. Conclusion Our hospital analgesic drugs with anesthesia basically reasonable, prescription management is still lacking, need to be further improved. Narcotic drugs are a kind of special management medicines. Physicians and pharmacists should strictly implement relevant regulations in accordance with the regulations to reduce the use of narcotic drugs and improve the quality of management of narcotic drugs.