解热镇痛药是许多家庭的常备药物,但本类药物诱发的不良反应在各类药物不良反应中占首位。发热是小儿患病时常出现的症状,有些家长在孩子发热时,随意给患儿服用成人用的解热镇痛成药。这样做既掩盖了症状,又容易发生不良反应,应引起重视。 小儿的肝、肾发育尚不成熟,肝脏的微粒体酶活性比成年人弱,葡萄糖醛酸的结合力差。药物进入人体后都需经肝 Antipyretics and analgesics are standing medicines in many families, but the adverse reactions induced by this class of drugs take the first place in the adverse reactions of various drugs. Fever is often the symptoms of children suffering from illness, some parents in children with fever, free to children taking children with antipyretic analgesics. Doing so covers up the symptoms, but also prone to adverse reactions, should pay attention. Pediatric liver and kidney development is not yet mature, liver microsomal enzyme activity is weaker than adults, glucuronic acid poor binding. After the drug into the body by the liver