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为评价乙型肝炎（HB）疫苗与DTP和口服脊髓灰质炎疫苗（OPV）同时接种的利弊,作者对626名婴儿于0、2、6月龄时各接种重组HB疫苗5μg,2、4、6月龄时加用DTP（不同部位注射）,并口服 OPV（Ⅰ组）。与此同时,对731名健康婴儿于2、4、6月龄仅免疫DTP和OPV,不接种HB疫苗作为对照（Ⅱ组）。末次免疫后40和60天,Ⅰ组和Ⅱ组各采集到590和329名幼儿的血标本,进行抗-HBs测定
To evaluate the pros and cons of simultaneous vaccination of hepatitis B (HB) vaccine with DTP and oral polio vaccine (OPV), the authors vaccinated 626 infants with recombinant HB vaccines at 0, 2, and 6 months of age at 5, Six months old plus DTP (different parts of the injection), and oral OPV (Ⅰ group). In the meantime, 731 healthy infants were immunized only with DTP and OPV at 2, 4, and 6 months of age and HB vaccines were not vaccinated as controls (group II). At 40 and 60 days after the last immunization, blood samples were collected from 590 and 329 infants in group I and group II for anti-HBs assay