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目的分析安徽省2000-2014年疫苗相关麻痹型脊髓灰质炎病例(VAPP)的流行病学特征。方法查阅2000-2014年安徽省VAPP的相关资料,用描述性流行病学研究方法,分析相关指标,找出其流行病学特征。结果 2000-2014年安徽省共报告46例VAPP,2003年和2011年发生的VAPP病例数最多,占15.22%和10.87%;服苗者VAPP与接触者VAPP发生年龄差异有统计学意义(χ~2=10.460,P<0.05);病毒学检测结果显示,脊灰疫苗Ⅱ型病毒株30例,较其他2种型别的检出率为高(χ~2=10.240,P<0.05)。结论在维持无脊髓灰质炎后期,应制定出科学,可行的免疫措施,以减少VAPP的发生。
Objective To analyze the epidemiological characteristics of vaccine-associated paralytic poliomyelitis (VAPP) from 2000 to 2014 in Anhui Province. Methods The data of VAPP in Anhui Province from 2000 to 2014 were consulted, and the descriptive epidemiological methods were used to analyze the related indicators and find out their epidemiological characteristics. Results A total of 46 cases of VAPP were reported in Anhui province from 2000 to 2014, with the highest number of VAPP cases in 2003 and 2011 accounting for 15.22% and 10.87%, respectively. There was significant difference in age of VAPP between VAPP and VAPP (χ ~ 2 = 10.460, P <0.05). The results of virological test showed that the detection rate of poliovirus type Ⅱ strains was higher than that of the other two types (χ ~ 2 = 10.240, P <0.05). Conclusion In the late stage of maintaining poliomyelitis, scientific and feasible immunization measures should be formulated to reduce the incidence of VAPP.