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目的:探讨放大染色内镜对结节性胃炎、胃粘膜相关组织淋巴瘤诊断的可行性。方法:选择哈尔滨医科大学第四临床医学院2007年5月～2010年7月诊断的结节性胃炎、疑诊胃粘膜相关组织淋巴瘤患者,观察临床、内镜、病理表现、幽门螺杆菌感染情况和根除治疗的效果。并应用日本FUJINON EG-590ZW型放大内镜对患者进行检查,观察根除幽门螺杆菌前后结节性胃炎、胃粘膜相关组织淋巴瘤的改变。结果:纳入分析的100例成人患者,男25例,女75例,年龄19～68岁,平均年龄39.2岁。主要临床表现为上腹痛和消化不良症状。内镜下表现为胃窦部为主,可扩展至胃体部的色泽均匀的结节样或颗粒样改变。病理检查显示胃窦部活检标本中有伴生发中心的淋巴滤泡增生。所有患者均有幽门螺杆菌感染,经根除治疗后,症状缓解率达92.0%。结论:结节性胃炎、胃粘膜相关组织淋巴瘤发生与幽门螺杆菌感染相关,放大染色内镜对结节性胃炎有诊断意义。
Objective: To investigate the feasibility of enlarged endoscopic diagnosis of nodular gastritis and gastric mucosa-associated tissue lymphoma. Methods: The diagnosis of nodular gastritis and suspected gastric mucosa-associated tissue lymphoma in the Fourth Clinical Medical College of Harbin Medical University from May 2007 to July 2010 were retrospectively analyzed. Clinical, endoscopic and pathological findings, Helicobacter pylori infection The situation and the effect of eradication therapy. Patients were also examined with magnifying endoscope FUJINON EG-590ZW in Japan to observe the changes of nodular gastritis and gastric mucosa-associated tissue lymphoma before and after eradication of Helicobacter pylori. Results: The 100 adult patients included in the analysis were 25 males and 75 females, aged 19-68 years with a mean age of 39.2 years. The main clinical manifestations of upper abdominal pain and indigestion symptoms. Endoscopic performance of the antrum-based, can be extended to the gastric body uniform nodular or pellet-like changes. Pathological examination showed antral biopsy specimens with lymphoid follicular hyperplasia associated with the center. All patients had Helicobacter pylori infection, after eradication therapy, the symptom relief rate was 92.0%. Conclusion: The incidence of nodular gastritis and gastric mucosa-associated lymphoma is related to Helicobacter pylori infection. Enlarged endoscopy has diagnostic value for nodular gastritis.