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在人胃内发现螺旋状微生物已有80余年历史,然而1975年才由 Steer 据组织切片及电镜所见,作出了较详细的描述.这种细菌见于80%胃溃疡病人的胃粘膜上皮细胞表面,因胃粘膜同时有中性粒细胞浸润,故可排除外界污染的可能性.基于该菌具有和其它弯曲菌属不同的特征,故1985年被正式命名为幽门弯曲菌(Campylobacter pylori-dis,简称 CP).近年来国外对 CP 的生物学、免疫学、致病性等方面已有较深入的研究,认为该菌在慢性胃炎,消化性溃疡的发生发展过程中具有重要意义.CP 的生物学特征、检查方法和致病性一、生物学特征CP 在光镜下呈革兰阴性,透射电镜与扫描电镜观察到 CP 为 C 形或 S 形细菌,长约2.5～3μm(最大可达6μm),直径0.5～0.7μm,螺旋周期0.9～1.2μm,菌体表面光滑,两端可见4～6根有鞘膜
Helical microbes have been found in the human stomach for more than 80 years, but were described in more detail by Steer histology and electron microscopy in 1975. This bacterium is found on the surface of gastric mucosal epithelial cells in 80% of gastric ulcer patients , Because of gastric mucosal neutrophil infiltration at the same time, it can rule out the possibility of contamination of the outside world.Based on the bacteria and Campylobacter has different characteristics, so in 1985 was officially named Campylobacter pylori-dis Referred to as CP) .In recent years, foreign CP on the biology, immunology, pathogenicity and other aspects have been more in-depth study, that the bacteria in chronic gastritis, peptic ulcer occurrence and development process is of great significance .CP biological Biological characteristics, inspection methods and pathogenicity First, the biological characteristics of CP was Gram-negative in light microscope, transmission electron microscopy and scanning electron microscopy observed CP C-shaped or S-shaped bacteria, about 2.5 ~ 3μm (up to 6μm ) Diameter of 0.5 ~ 0.7μm, spiral period of 0.9 ~ 1.2μm, cell surface smooth, visible at both ends of 4 to 6 have a sheath