论文部分内容阅读
目的超声观察长期小剂量米非司酮对子宫内膜的影响及声像图特征。方法对36例子宫肌瘤、子宫腺肌症及子宫内膜异位症术后患者给予连续口服米非司酮10 mg/d 6个月,于3个月及6个月分别进行阴道超声检查。结果长期服用小剂量米非司酮6个月,发现子宫内膜随服药时间的增长而逐渐增厚,内膜回声偏强分布欠均宫腔内三条线结构不清,多伴有多个大小不等的小囊状回声,服药时间越长,小囊状改变发生率越高。结论米非司酮对子宫内膜的影响随着用药持续时间不同而差异明显,长时间应用子宫内膜可以增生,尤其以囊腺型增生为明显。
Objective To observe the effects of long-term and low-dose mifepristone on the endometrium and sonographic features. Methods Thirty-six patients with uterine leiomyoma, adenomyosis and endometriosis were given continuous oral mifepristone 10 mg / d for 6 months. Vaginal ultrasonography was performed at 3 months and 6 months respectively . Results Long-term use of small doses of mifepristone 6 months and found that the endometrium gradually increased with the growth of medication time, endometrial echo partial distribution of intrauterine less than three lines are unclear, mostly accompanied by multiple sizes Ranging from small cystic echo, the longer the medication, the higher the incidence of small cystic changes. Conclusion The effect of mifepristone on the endometrium varies significantly with the duration of treatment. Prolonged application of endometrial hyperplasia, especially in cystadenocular hyperplasia, is obvious.