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目的分析比较3种不同麻醉剂对长爪沙鼠的麻醉效果。方法成年长爪沙鼠分为3组,分别腹腔注射水合氯醛、乌拉坦和戊巴比妥生理盐水溶液,观察麻醉诱导时间、麻醉期、苏醒时间及心率和呼吸变化,并与大、小鼠进行比较。结果长爪沙鼠在注射水合氯醛后麻醉保持时间最长,而乌拉坦最短。水合氯醛对呼吸和心跳的抑制能力较弱于乌拉坦和戊巴比妥。除了乌拉坦,其余两种药物对长爪沙鼠的麻醉时间均较大,小鼠更长一些。结论3种麻醉药对长爪沙鼠的麻醉效果明显不同,对其呼吸和心跳频率的影响也有差别,可以根据不同的实验要求选用这三种麻醉剂。相对于大、小鼠来说,长爪沙鼠对3种麻醉剂都更敏感。
Objective To compare and analyze the anesthetic effects of three different anesthetics on Mongolian gerbils. Methods Adult Mongolian gerbils were divided into 3 groups: intraperitoneal injection of chloral hydrate, urethane and pentobarbital saline solution, induction of anesthesia induction, anesthesia, recovery time and heart rate and respiratory changes, and large and small Rats were compared. Results Mongolian gerbils had the longest anesthesia retention time and the lowest urethane time after chloral hydrate injection. Chloral hydrate on respiratory and heart rate is weaker than urethane and pentobarbital. In addition to urethane, the remaining two drugs anesthetized gerbil longer, and the mice grew longer. Conclusion The anesthetic effect of three kinds of anesthetics on Meriones unguiculatus is obviously different, and the effects on respiration and heart rate are also different. These three kinds of anesthetics can be selected according to different experimental requirements. Mongolian gerbils are more sensitive to all 3 anesthetics than large mice.