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目的:对母婴丙型肝炎病毒血清抗体进行检测,观察酶联免疫吸附法ELISA检查效果。方法:选取本院呈现抗-HCV阳性的新生儿及产妇血清样本730份、供血员血清样本566份,应用ELISA检测指标对新生儿及产妇指标进行观察。结果:ELISA检测结果 HBsAg(+)与HBsAg(-)母婴抗-HCV间存在明显差异(P<0.05),肝功能异常与HBsAg(+)产妇具有直接联系(P<0.05),抗-HCV阳性率随着年龄的增长而上升(P<0.05),具有统计学意义。结论:ELISA能够准确诊断丙型肝炎病毒感染状况,可以直接确诊有无母婴之间的垂直传播,对新生儿身体健康具有至关重要的作用。
Objective: To detect the serum antibody of hepatitis C virus (HCV) in maternal and infant and observe the effect of enzyme-linked immunosorbent assay (ELISA). Methods: We selected 730 neonates and maternal serum samples positive for anti-HCV in our hospital and 566 serum samples from blood donors. The neonatal and maternal indicators were observed by ELISA. Results: There was a significant difference (P <0.05) between anti-HCV and HBsAg (+) in maternal and neonatal HBsAg (+) patients. There was a direct correlation between abnormal liver function and HBsAg (+ The positive rate increased with age (P <0.05), with statistical significance. Conclusion: ELISA can accurately diagnose the status of hepatitis C virus infection, which can be directly diagnosed whether there is vertical transmission between mother and baby, which plays an important role in the health of the newborn.