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目的:观察自拟扶正抑癌方配合泰勒宁片对中重度癌性疼痛的镇痛效果以及对患者生存质量和免疫功能的影响。方法:将50例中重度癌性疼痛患者随机分成2组各25例。治疗组给予自拟扶正抑癌方配合口服泰勒宁片治疗;对照组单纯给予泰勒宁片治疗。结果:治疗组与对照组疼痛缓解总有效率分别为96.0%和92.0%,2组比较,差异无显著性意义(P>0.05);2组治疗后Karnofsky评分及T淋巴细胞亚群水平均有改善,差异有显著性或非常显著性意义(P<0.05,P<0.01);2组治疗后不良反应程度比较,差异有非常显著性意义(P<0.01)。结论:自拟扶正抑癌方可以提高患者生活质量及免疫功能,有效减轻泰勒宁片的不良反应,其配合泰勒宁片治疗中重度癌性疼痛具有较好的临床效果。
OBJECTIVE: To observe the analgesic effect of self-made Fuzheng Suppressing Decoction in combination with Taylor’s Tablet on moderate to severe cancerous pain and its effect on the quality of life and immune function of patients. Methods: Fifty patients with moderate-severe cancerous pain were randomly divided into two groups of 25 cases each. The treatment group was given self-made righting suppression cancer with oral treatment of Taylor Ning tablets; the control group was treated with Taylor’s pill alone. Results: The total effective rate of pain relief in treatment group and control group was 96.0% and 92.0% respectively, there was no significant difference between the two groups (P> 0.05); Karnofsky score and T lymphocyte subsets There was significant difference between the two groups (P <0.05, P <0.01). There was significant difference between the two groups in the degree of adverse reactions after treatment (P <0.01). CONCLUSION: Self-made Fangzheng Tiaohou decoction can improve the quality of life and immune function of patients and effectively reduce the adverse reaction of Tailing tablets. It has good clinical effect in combination with Tailing tablets in the treatment of moderate-severe cancerous pain.