国内、外对泪道功能的测定方法及其试剂研究甚多,但对泪道功能检查在临床上的应用价值,特别是在早期诊断、早期预防性治疗上研究甚少。作者根据Jones(1966)的鼻腔收集染料法及Norn’s(1965)苦味试验的原理,采用2%红汞+氯霉素混和液测定泪液自然导流功能,并对其结果进行综合分析,以探讨其临床应用及预防治疗的价值,提出了临床前期这一概念。资料与方法 Domestic and foreign methods of determination of lacrimal duct function and reagents are many, but lacrimal duct function test in the clinical application of value, especially in the early diagnosis, early preventive treatment of little research. According to Jones (1966) nasal collection dye method and Norn’s (1965) bitterness test principle, using 2% mercuric chloride + chloramphenicol mixed fluid determination tear natural drainage function, and the results of a comprehensive analysis to explore its Clinical application and the value of prevention and treatment, put forward the concept of preclinical. Materials and Methods