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目的探讨硒酵母片联合膦甲酸钠氯化钠注射液治疗带状疱疹的临床疗效。方法选取2013年5月—2014年7月河北北方学院附属第一医院收治的带状疱疹患者84例,随机分为治疗组与对照组,各42例。对照组患者予以膦甲酸钠氯化钠注射液治疗,治疗组患者在对照组基础上加用硒酵母片治疗。观察两组患者临床疗效及不良反应发生情况。结果治疗组患者总有效率高于对照组,差异有统计学意义(P<0.05);两组患者均未发生严重不良反应。结论硒酵母片联合膦甲酸钠氯化钠注射液治疗带状疱疹的临床疗效显著,且不良反应少。
Objective To investigate the clinical efficacy of selenium yeast tablets and foscarnet sodium chloride injection in the treatment of shingles. Methods From May 2013 to July 2014, 84 patients with herpes zoster admitted to the First Affiliated Hospital of Hebei North University were selected and randomly divided into treatment group and control group, with 42 cases in each group. Patients in the control group were treated with sodium foscarnet sodium chloride injection. Patients in the treatment group were treated with selenium yeast tablets on the basis of the control group. The clinical efficacy and adverse reactions of the two groups were observed. Results The total effective rate of the treatment group was higher than that of the control group (P <0.05). No serious adverse reactions occurred in both groups. Conclusion Selenium yeast tablets combined with sodium fonfonate sodium chloride injection in the treatment of herpes zoster clinical significant effect, and less adverse reactions.