慢性阻塞性肺疾病(慢阻肺,COPD)是多种病因引起的慢性气道阻塞,其主要病理生理改变为:阻塞性通气功能障碍,后期发展为肺动脉高压、肺心病.慢阻肺肺动脉血栓形成率达20～50%,合并严重肺动脉高压者血栓形成率更高.血小板具有粘附、促凝和收缩血块的功能,因此在血栓形成和血管损伤中起重要作用. Chronic obstructive pulmonary disease (COPD) is a chronic obstructive airway obstruction caused by a variety of causes. The main pathophysiological changes are obstructive ventilatory dysfunction, late development of pulmonary hypertension, pulmonary heart disease, chronic obstructive pulmonary disease The formation rate of 20 ~ 50%, combined with severe pulmonary hypertension in patients with higher rates of thrombosis.Platelets have adhesion, procoagulant and systolic blood clots and therefore play an important role in thrombosis and vascular injury.