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重症病毒性肝炎患者中80%发生暴发性肝功能衰竭和肾功能衰竭,但轻症病毒性肝炎患者发生肾功能衰竭者则尚未见报道,本文报告12例急性病毒性肝炎患者发生严重的肾功能衰竭。 12例中8例为男性,年龄20～60岁,其中2例为孕妇,每例都有急性病毒性肝炎的典型临床表现,其中2例HBsAg阳性;另1例于2月前曾输血,HBsAg阴性,故可能为“非甲、非乙”型肝炎;其余9例中3例测得甲型肝炎抗体。12例均无服用对肾脏有毒性的药物史。12例血液生化测定均显示有不同程度的血清胆红素和酶值升高伴不同程度的凝血酶原时
Severe viral hepatitis in 80% of patients with fulminant hepatic failure and renal failure, but patients with mild viral hepatitis in patients with renal failure have not been reported, the report of 12 cases of acute viral hepatitis in patients with severe renal function Failure. Of the 12 cases, 8 were male and 20 to 60 years of age, 2 of whom were pregnant women. Each case had the typical clinical manifestation of acute viral hepatitis, of which 2 were HBsAg positive; the other 1 had blood transfusion 2 months ago and HBsAg Negative, it may be “non-A, non-B” hepatitis; the remaining 9 cases in 3 cases of hepatitis A antibodies were measured. None of the 12 patients had a history of drug toxicity to the kidneys. 12 cases of blood biochemical tests showed different levels of serum bilirubin and enzyme values increased with varying degrees of prothrombin