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目的:回顾性分析青年中高危不稳定型心绞痛(UAP)患者早期冠状动脉介入治疗(PCI)的近期疗效。方法:将25例青年中高危UAP(TIMI危险评分≥3分)患者,分为早期PCI组(14例)和延迟PCI组(11例)。观察2组患者术中病变情况、血栓负荷、记录30 d内心脏事件(包括心绞痛、急性心肌梗死、猝死、再次PCI及冠状动脉搭桥手术)的发生率及住院时间等。结果:2组冠状动脉病变及PCI情况相似,早期PCI组血栓负荷相对较多。与延迟PCI组相比,早期PCI组能降低30 d内心绞痛发生率,能够缩短症状缓解及住院时间(P<0.05)。结论:对于青年中高危UAP患者应该优先选择早期PCI。
Objective: To retrospectively analyze the short-term effect of early coronary intervention (PCI) in young patients with unstable angina (UAP). Methods: Twenty-five young patients with high-risk UAP (TIMI risk score ≥3) were divided into two groups: early PCI group (n = 14) and delayed PCI group (n = 11). The incidence of intraoperative lesions, thrombus burden and the incidence of cardiac events (including angina pectoris, acute myocardial infarction, sudden death, PCI and coronary artery bypass grafting) within 30 days and the length of hospital stay were recorded. Results: The coronary lesions in both groups were similar to those in PCI. The thrombus load in the early PCI group was relatively high. Compared with the delayed PCI group, the early PCI group could reduce the incidence of angina within 30 days and shorten the symptom relief and hospital stay (P <0.05). CONCLUSIONS: Early PCI should be given to high-risk UAP patients in young adults.