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目的探讨耐多药肺结核继发肺部真菌感染的危险因素、临床特点及诊治方法,以提高对2病并存时临床表现的认识和综合处理的能力。方法回顾湖北黄石市二医院2002年以来收治的51例耐多药肺结核合并肺部真菌感染的病历资料,并进行分析。结果合并肺部真菌感染的耐多药肺结核均有明显易感因素,其临床特点:结核病史长;复治病例多;年龄偏大;肺部病变广泛,空洞多,病情较重;主要致病真菌为念珠菌。结论耐多药肺结核易继发肺部真菌感染,提高对2病并存的认识,有利于耐多药肺结核病的控制及降低死亡率。
Objective To investigate the risk factors, clinical features, diagnosis and treatment of pulmonary fungal infection in multidrug-resistant pulmonary tuberculosis in order to improve the understanding of the clinical manifestations and the ability of comprehensive treatment. Methods The records of 51 cases of multidrug - resistant pulmonary tuberculosis complicated with pulmonary fungal infection admitted to the Second Hospital of Huangshi, Hubei Province since 2002 were reviewed and analyzed. Results The multidrug-resistant pulmonary tuberculosis complicated with pulmonary fungal infection had obvious predisposing factors. The clinical features were as follows: the history of tuberculosis was long; there were many cases of retreatment; the age was too large; the lungs were extensive, empty and serious; the main pathogenic Fungi Candida. Conclusions Multidrug-resistant pulmonary tuberculosis is likely to cause secondary fungal infections of the lungs and enhance the understanding of the co-existence of the two diseases, which is conducive to the control of multi-drug resistant pulmonary tuberculosis and reduce the mortality rate.