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目的探讨DCE-MRI定量和半定量参数对时间-信号强度曲线表现为平台型前列腺癌灶和前列腺增生的鉴别诊断价值。方法回顾性分析48例时间-信号强度曲线呈平台型的前列腺疾病患者(前列腺癌26例,前列腺增生22例)DCE-MRI定量和半定量参数,包括容积转移常数(K~(trans))、转移速率常数(K_(ep))、血管外细胞外间隙容积分数(V_e),血容量(BV)、血流量(BF)、达峰时间(TTP)。并运用SPSS进行统计学分析。结果在DCE-MRI时间-信号强度曲线为平台型的前列腺癌灶组和前列腺增生组Ktrans、Kep、BF值分别为(2.33±0.93)min~(-1)和(1.21±0.71)min~(-1)、(3.46±1.41)min~(-1)和(1.81±0.85)min~(-1)、(182.63±74.79)ml·g~(-1)·min~(-1)和(140.88±50.73)ml·g~(-1)·min~(-1),组间差异均有统计学意义(P<0.05)。结论 K~(trans)、K_(ep)、BF值在前列腺癌灶组和前列腺增生组间差异存在统计学意义,DCE-MRI定量和半定量参数对平台型时间-信号强度曲线的前列腺癌灶和前列腺增生间的鉴别具有一定的价值。
Objective To investigate the differential diagnostic value of quantitative and semi-quantitative parameters of DCE-MRI in differential diagnosis of benign prostatic hyperplasia and benign prostatic hyperplasia with time-signal intensity curve. Methods The quantitative and semi-quantitative DCE-MRI quantitative and semi-quantitative data of 48 patients with prostate cancer (26 cases of prostate cancer and 22 cases of benign prostatic hyperplasia) with time-signal intensity curve were retrospectively analyzed, including volume transfer constant (K trans) Transfer rate constant (K ep), extracellular extracellular space volume fraction (V_e), blood volume (BV), blood flow (BF) and peak time (TTP) were calculated. And use SPSS for statistical analysis. Results The Ktrans, Kep, and BF values of the prostate cancer group and benign prostatic hyperplasia group were (2.33 ± 0.93) min ~ (-1) and (1.21 ± 0.71) min ~ -1, (3.46 ± 1.41) min ~ (-1) and (1.81 ± 0.85) min ~ (-1), (182.63 ± 74.79) ml · g ~ (-1) · min ~ 140.88 ± 50.73) ml · g ~ (-1) · min ~ (-1) respectively. There was significant difference between the two groups (P <0.05). Conclusion There are significant differences in K trans, K ep and BF between prostatic hyperplasia and benign prostatic hyperplasia. The quantitative and semi-quantitative parameters of DCE-MRI have no significant difference between the Prostate foci And the identification of benign prostatic hyperplasia has some value.