论文部分内容阅读
用Ｙ型迷宫箱测试小鼠空间分辨能力，结果：ｐｏ －硒化卡拉胶（ －ｓｅｌｅｎｏｃａｒｒａｇｅｅ－ｎａｎ， －ＳｅＣ）１８０ｍｇ／ｋｇ及１０８ｍｇ／ｋｇ（ｑｄ×１４ｄ）能增强正常小鼠的学习能力，提高学习成绩；ｐｏ －ＳｅＣ１８０、１０８及６４ｍｇ／ｋｇ（ｑｄ×１４）对东莨菪碱（ｉｐ４ｍｇ／ｋｇ）所致小鼠学习障碍均有拮抗作用；ｐｏ －ＳｅＣ１８０ｍｇ／ｋｇ（ｑｄ×１４）对东莨菪碱（ｉｐ５ｍｇ／ｋｇ）所致小鼠记忆保持障碍有改善作用。以上表明 －ＳｅＣ对脑的学习功能有促进作用，并能拮抗药物引起的学习与记忆功能的损害，改善大脑功能．
The spatial resolution of mice was tested by Y-maze box. The results showed that po-selenocarragee-nanocapsules 180mg / kg and 108mg / kg (qd × 14d) could enhance the learning ability of normal mice, (P <0.05); po-SeC180, 108 and 64mg / kg (qd × 14) had antagonistic effects on scleramphetamine-induced mice learning disorders; po-SeC180mg / / Kg) can improve memory retention disorder in mice. The above shows that -SeC can promote learning function of brain and antagonize the damage of learning and memory function caused by drugs and improve brain function.