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目的通过分析糖尿病患者发生糖尿病视网膜病变(DR)的相关危险因素,以达到预防和治疗早期DR的目的。方法对2821例糖尿病患者进行全面眼科检查,抽血检测:空腹血糖、甘油三脂、糖化血红蛋白;尿微量蛋白检验;测量血压;体重指数检查;询问病程。运用SPSS13.0软件进行统计分析,计数资料比较采用卡方χ2检验;DR与各种影响因素间相关性检验用Logistic回归分析,分别进行单因素和多因素回归分析。结果 DR的发生与性别、年龄、糖尿病病程、空腹血糖、糖化血红蛋白、体重指数、血压、甘油三脂、尿微量蛋白存在明显相关性(P<0.05);糖尿病病程、空腹血糖、糖化血红蛋白、甘油三脂、尿微量蛋白是DR的独立危险因素。结论 DR的发病是多因素作用的结果,应重视并加强糖尿病危险因素的防治,降低DR的发病率。
Objective To analyze the risk factors of diabetic retinopathy (DR) in diabetic patients so as to achieve the purpose of preventing and treating early DR. Methods A total of 2821 patients with diabetes were examined by ophthalmology. The blood tests were: fasting blood glucose, triglycerides, glycosylated hemoglobin; urine microalbumin test; blood pressure; body mass index examination; SPSS13.0 software was used for statistical analysis. Chi-square test was used to compare the count data. Logistic regression analysis was used to test the correlation between DR and various influencing factors. Univariate and multivariate regression analyzes were performed respectively. Results There was a significant correlation between the occurrence of DR and gender, age, duration of diabetes, fasting blood glucose, glycosylated hemoglobin, body mass index, blood pressure, triglyceride and urine microalbumin (P <0.05); duration of diabetes, fasting blood glucose, glycosylated hemoglobin, Triglyceride, urinary micro-protein is an independent risk factor for DR. Conclusions The incidence of DR is the result of multi-factor effect. It should pay attention to and strengthen the prevention and treatment of diabetes risk factors and reduce the incidence of DR.