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目的:探讨接种乙肝疫苗后儿童乙肝发病特征及变化情况。方法:将1995年以来在我院接种乙肝疫苗的10000例儿童为实验对象,观察分析所有儿童在接种乙肝疫苗后的15年内,乙肝的发病特征和发病率的变化情况。结果:经过观察和分析发现,接种乙肝疫苗的儿童,其乙肝发病率会随着时间的递增而逐渐下降,且接种乙肝后儿童的流行特征发生了显著的改变,其中,10岁以下的儿童发病率变化最为显著。讨论:本次临床实践的结果显示,接种乙肝疫苗能够有效降低儿童乙肝的发病率,改变儿童的流行特征,因此,我国应进一步扩大乙肝疫苗的接种范围,从而有效控制甚至消除儿童乙肝疾病。
Objective: To investigate the characteristics and changes of hepatitis B in children after hepatitis B vaccination. Methods: 10000 cases of hepatitis B vaccine in our hospital since 1995 were used as experimental subjects. The incidence and incidence of hepatitis B in all children were observed and analyzed within 15 years after inoculation of hepatitis B vaccine. Results: After the observation and analysis, the incidence of hepatitis B in children vaccinated with hepatitis B vaccine decreased gradually with time, and the prevalence of children with hepatitis B after hepatitis B vaccination significantly changed. Among them, children under 10 years of age Rate changes the most significant. Discussion: The results of this clinical practice show that hepatitis B vaccine can effectively reduce the incidence of hepatitis B in children and change the epidemiological characteristics of children. Therefore, we should further expand the coverage of hepatitis B vaccination in order to effectively control or even eliminate hepatitis B in children.