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经鼻腔穿刺向脑下垂体注射酒精治疗晚期恶性肿瘤患者疼痛法,系1968年由Moricca氏所提出,虽其机制尚不清楚,但效果肯定。作者们曾应用此法于5例头颈部癌患者,包括舌癌、颈部恶性黑瘤、左扁桃体癌、左上颌癌和双上颌癌各1例。他们均曾接受过各种抗癌治疗未曾奏效,局部复发且有远处转移;同时诉局部和全身剧痛,对此虽投予了麻醉药“镇痛新”(pentazoeine),甚至应用了硬膜外阻滞治疗,亦未能完全止痛。但经此法治疗后获得了较好效果,且见效
The method of intranasal pituitary injection with alcohol to treat pain in patients with advanced malignant tumors was proposed by Moricca in 1968. Although the mechanism is not clear, the effect is certain. The authors have applied this method to 5 cases of head and neck cancer patients, including tongue cancer, cervical malignant melanoma, left tonsil cancer, left maxillary carcinoma, and double maxillary carcinoma each. All of them had received various anti-cancer treatments that did not work and had local recurrence and distant metastases. At the same time, they complained of local and systemic pain. Although this was administered to the narcotics “pentazoeine” (pentazoeine), even hard Extra-membrane block treatment also failed to completely relieve pain. However, after this treatment, better results were obtained and effective