三峡库区涪陵段1964至1993年肾综合征出血热的流行趋势

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本文对三峡库区涪陵段1964~1993年肾综合征出血热(HFRS)的流行趋势作了某些分析,旨在兴建、开发三峡库区时为防治本病提供一定的依据。30年中发病乡(镇)的扩大与发现,以1964~1969年较为突出,占累计发病乡(镇)总数的27.59%,在嗣后的24年(1970~1993年)间仍以平均每年3.8个疫区的新发现渐进式扩大,可见三峡库区涪陵段HFRS疫区的发现与扩大仍未结束;发病率在80年代(6.58/10万)急剧上升,较60年代(3.53/10万)和70年代(2.51/10万)发病总数高1.83倍,90年代的发病率(1O.54/10万)较前26年上升57.49%;病例围绕高、中发疫区向心性集中,流行强度则离心性递减;在涪陵段的长江南岸、乌江北岸以集簇性暴发为主,长江北岸、乌江南岸为散在发病;呈5~7月(占27.03%)、10~12月(占45.79%)“双峰”型季节性发病高峰,1~4、8、9月份为非流行季节,其病例占总发病数的27.17%;每5~7年出现l次周期性发病高峰,高峰年的发病率与该地区整体发病率一致,似呈上升趋势;68.76%的病人集中在20~49岁人群,农民发病占83.35%,男女之比为2.5:1。疫区及疫源地以野鼠型为主,混合型次之,家鼠型也存在。 This article made some analyzes on the epidemic trend of hemorrhagic fever with renal syndrome (HFRS) from 1964 to 1993 in the Fuling section of the Three Gorges Reservoir Area, aiming to provide some evidences for the prevention and treatment of this disease in the construction and development of the Three Gorges Reservoir Area. The expansion and discovery of the affected townships (towns) in the past 30 years were more prominent from 1964 to 1969, accounting for 27.59% of the total number of townships (towns) affected. In the ensuing 24 years (1970 to 1993), the average annual growth rate was 3.8 The discovery of the epidemic area of ​​HFRS in Fuling of the Three Gorges Reservoir Area has not yet ended yet. The incidence rate rose sharply in the 1980s (6.58 / 100,000) compared with that in the 1960s (3.53 / 100,000) And 1.83 times of the total incidence in the 1970s (2.51 / 100000). The incidence rate in the 1990s (10.54 / 100000) was 57.49% higher than that in the previous 26 years. The cases focused on the concentricity and epidemic intensity (P <0.05), and then decreased with the decrease of the centrifugal force. In the Fuling section of the southern bank of the Yangtze River, the northern bank of the Wujiang River was dominated by a cluster of outbreaks. The north bank of the Yangtze River and the southern bank of the Wujiang River were scattered. ) “Bimodal” type seasonal peak, 1-4,8,8 month non-epidemic season, the number of cases accounted for 27.17% of the total number of cases; every 5 to 7 years appeared once the incidence of cyclical peak, peak year The incidence is in line with the overall incidence in the region and appears to be on the rise; 68.76% of patients In the 20 to 49 year-olds, the incidence farmers accounted for 83.35%, male to female ratio was 2.5: 1. Outbreaks and foci to the wild-based mouse type, followed by mixed type, there are also domestic mouse type.
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